Publications

31. Ludwig, L.M., Roach, L.E., Katz, S.G.,  LaBelle, J.L. (2020) Loss of BIM in T Cells Results in BCL-2 Family BH3-member Compensation but Incomplete Cell Death Normalization. Apoptosis. 10.1007 ahead of print. Ludwig, et al. 2020

30. Kothari, S., Artz, A.S., Lee, S.M., Fulton, N., Park, J-H., Stock, W., Larson, R.A., Odenike, O., Kline, J., LaBelle, J., Kosuri, S., Riedell, P., Nakamura, Y., Bishop, M.R., Liu, H. (2020) Dose Escalation Prophylactic Donor Lymphocyte Infusion After T-cell Depleted Matched Related Donor Allogeneic Hematopoietic Cell Transplantation Is Feasible and Results in Higher Donor Chimerism, Faster Immune Re-constitution, and Prolonged Progression-Free Survival. Bone Marrow Transplantation. 10:1038; ahead of print. Kothari, et al. 2020

29. Hadji, A., Schmitt, G. K., Schnorenberg, M. R., Roach L., Hickey, C.M., Leak, L.B., Tirrell, M.V., LaBelle, J.L. (2019) Preferential Targeting of MCL-1 by a Hydrocarbon-Stapled BIM BH3 Peptide. Oncotarget. 10:6219-6233. Hadji, et al. 2019

28. Schnorenberg, M.R.*, Bellairs, J.A.*, Samaeekia, R., Acar, H., Tirrell, M. V., LaBelle, J.L. (2019) Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal Release. Materials. 12(16). 2567. Schnorenberg and Bellairs, et al. 2019

27. Fan Y., Artz, A.S., van Besien, K., Stock, W., Larson, R.A., Odenike, O., Godley, L.A., Kline, J., Cunningham, J.M., LaBelle, J.L., Bishop, M.R., Liu, H. (2019) Outcomes Following Second Allogeneic Stem Cell Transplantation for Disease Relapse after T Cell Depleted Transplant Correlate with Remission Status and Remission Duration after the First Transplant. Experimental Hematology & Oncology. 8:1. Fan, et al. 2019

26. Ludwig, L.M., Maxcy, K., LaBelle, J.L. (2019) Flow cytometry-based detection and analysis of BCL-2 family proteins and mitochondrial outer membrane permeabilization (MOMP). Methods in Molecular Biology1877:77-91. Ludwig, et al. 2019

25. Schnorenberg, M.R., Yoo, Sang Pil, Tirrell, M.V., LaBelle, J.L. (2018) Synthesis and purification of homogenous lipid-based peptide nanocarriers by overcoming phospholipid ester hydrolysis. ACS Omega. 3(10):14144-14150. Schnorenberg, et al. 2018

24. Nassin, M.L., Nicolaou, E., Gurbuxani, S., Cohn, S.L., Cunningham, J.M., LaBelle, J.L. (2018) Immune reconstitution following autologous stem cell transplantation in patients with high-risk neuroblastoma at the time of ch14.18 mAb immunotherapy. Biology of Blood and Marrow Transplantation. 24(3):452-459. Nassin, et al. 2018

23. Acar, H., Ting, J.M., Srivastava, S., LaBelle, J.L.,Tirrell, M.V. (2017) Molecular Engineering Solutions for Therapeutic Peptide Delivery. Chemical Society Reviews. 46(21):6553-6569. Acar, et al. 2017

22. Acar, H., Samaeekia, R., Schnorenberg, M. R., Tirrell, M. V., LaBelle, J.L. (2017) Cathpesin-mediated cleavage of peptides from peptide amphiphiles leads to enhanced intracellular peptide accumulation. Bioconjugate Chemistry. 28(9): 2316-2326. Acar, et al. 2017

21. Pu, Jinyue, Dewey, J.A., Hadji, A., LaBelle, J.L.,Dickinson, B.C. (2017) RNAP tags to monitor multidimensional protein-protein interactions reveal pharmacological engagement of Bcl-2  proteins. Journal of the American Chemical Society. 139(34):11964-11972. Pu, et al. 2017

20. Nassin, M., Virgilio, J., Heeney, M., LaBelle, J.L. (2017) Neonatal Anemia: Revisiting the Enigmatic Pyknocyte. American Journal of Hematology. 92(7):717-721. Nassin, et al. 2017

19. Ludwig, L., Nassin, M., Hadji, A., LaBelle, J.L. (2016) Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation. Frontiers in Pediatrics; Pediatric Hematology and Hematological Malignancies. 4:135. Ludwig, et al. 2016

18. Acar, H., Srivastava, S., Chung, E., Schnorenberg, M.R., Barett, J.C., LaBelle, J.L.,Tirrell. (2016) Self-Assembling Peptide-Based Building Blocks in Medical Applications. Advanced Drug Delivery Reviews. 110-111:65-79. Acar, et al. 2016

17. Darlington, W.S., Pinto, N., Hecktman, H., Cunningham, J.M., Cohn, S.L., LaBelle, J.L. (2015) Stem Cell Transplant-Associated Wernicke Encephalopathy in a Patient with Stage 4, High-Risk Neuroblastoma. Pediatric Blood and Cancer. 62(12):2232-2234. Darlington, et al. 2015

16. Diamond, C. E., Sanchez, M.J., LaBelle, J.L. (2015) Diagnostic Criteria and Evaluation of Severe Combined Immunodeficiency in the Neonate. Pediatric Annals. 44(7):181-187. Diamond, et al. 2015

15. Reynolds, C., Roderick, J., LaBelle, J.L., Bird, G., Mathieu, R., Bodaar, K., Colon, D., Pyati, U., Stevenson, K., Qi, J., Harris, M., Silverman, L., Sallan, S., Bradner, J.E., Neuberg, D.S., Look, A.T., Walensky, L., Kelliher, M.A., Gutierrez, A. (2014) Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia. Leukemia. 28:1819-1827. Reynolds, et al. 2014

14. Bird, G., Gavathiotis, E., LaBelle, J.L., Katz, S.G., Walensky, L.D. (2014) Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies. Journal of the American Chemical Society. 9(3):831-837. Bird, et al. 2014

13. Katz, S.G., LaBelle, J.L., Valeriano, R.P., Fisher, J.K., Walensky, L.D. (2014) Mantle Cell Lymphoma in Cyclin D1 Transgenic Mice with Bim-deficient B-cells. Blood.123 (6):884-893. Katz, et al. 2014

12. Meserve, EE, Lehmann, L., Perez-Atayde, A.R., LaBelle, J.L. (2014) Cyclophosphamide-Associated Cardiotoxicity in a Child following Stem Cell Transplantation for β-Thalassemia Major: Case Report and Review of the Literature. Pediatric Developmental Pathology. 17(1):50-54. Meserve, et al. 2014

11. LaBelle, J.L.and Cunningham, J.M. (2013) Stem Cell Transplant as an Immunomodulatory Tool for Children with Hematological Malignancies. ASCO Educational Book. e347. LaBelle and Cunningham. 2013

10. Edwards, A. L., Gavathiotis, E., LaBelle, J.L.,Braun, C. R., Opoku-Nsiah, K., Bird, G.H., Walensky, L.D. (2013) Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3. Chemistry & Biology. 20:888-902. Edwards, et al. 2013

9. LaBelle, J.L.,Katz, S.G., Bird, G.H., Gavathiotis, E., Stewart, M.L., Lawrence, C., Fisher, J.K., Godes, M., Pitter, K., Kung, A.L., Walensky, L, D. (2012) A Stapled BIM Peptide Overcomes Apoptotic Resistance in Hematologic Cancers. Journal of Clinical Investigation. 122(6):2018-2031.

8. Pitter, K., Bernal, F., LaBelle, J.,Walensky, L.D. (2008) Dissection of the BCL-2 Family Signaling Network by Use of Stabilized a-Helices of BCL-2 Domains. Methods in Enzymology. 446:387-408. Pitter, et al. 2008

7. Gutweiler, J., LaBelle, J., Suh, M., Misra, M., Ahmed, M., Lee, E., Vargas, S., Kim, H., Weldon, C. (2008) A Familial Case of Pleuropulmonary Blastoma. European Journal of Pediatric Surgery. 18:192-194. Gutweiler, et al. 2008

6. Fishman, D.S, Manfredi, M.A, LaBelle, J.L, Levine, J.E., Shamberger, R.C., Rufo, P.A. (2007) Pancreatitis as the Initial Manifestation of Stage IV Neuroblastoma-A Case Report. Journal of Pediatric Gastroenterology and Nutrition. 44:146-148. Fishman, et al. 2007

5. Rosenblum, M. D., LaBelle, J.L., Chang, C.C., Margolis, D. A., Schauer, D. W., Vesole, D. H. (2004) Efficacy of Alemtuzumab Treatment for refractory T Cell Large Granular Lymphocytic Leukemia. Blood103(5);1969-1971. Rosenblum, et al. 2004

4. LaBelle, J.L. and Truitt, R.L. (2002) Characterization of a Murine NKT Cell Tumor Previously Described as an Acute Myelogenous Leukemia. Leukemia and Lymphoma. 43(8):1637-1644. LaBelle, et al. 2002b

3. LaBelle, J.L., Hanke, C.A., Blazar, B.R., Truitt, R.L. (2002) Negative Effect of CTLA-4 In Vivo on Induction of T-cell Immunity to B7-1+, but not B7-2+, Murine Acute Myelogenous Leukemia. Blood. 99(6):2146-2153. LaBelle, et al. 2002a

2. Johnson, B.D., Becker, E.B., LaBelle, J.L., Truitt, R.L. (1999) Role of Immunoregulatory Donor T Cells in Suppression of Graft-Versus-Host Disease Following Donor Leukocyte Infusion Therapy. Journal of Immunology. 163:6479-6487.  Johnson, et al. 1999

1. LaBelle, J. L., Dutton, K.G., Maravolo, N.C. (1997) The Influence of Ethylene and Spermine on Phosphatase Activity During Senescence in Marchantia Polymorpha. International Journal of Plant Science158:552-555. LaBelle, et al. 1997